The Great Healthcare Disruption: Big Tech, Bold Policy, and the Future of American Medicine

5 Star Review

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Editorial Book Review:

By SB Borcy

Marschall Runge's The Great Healthcare Disruption is a timely and authoritative examination of the significant changes that are transforming American medicine. He encapsulates the urgency, complexity, and potential of a healthcare system that is undergoing a significant transformation with uncommon depth and clarity. This is not merely a book; it is a guide for navigating the intersection of technology, policy, and medicine in the 21st century.

Runge's writing is profoundly informed, accessible, and razor-sharp. He seamlessly integrates real-world case studies with insider insights, providing the reader with a comprehensive understanding of complex systems without sacrificing nuance. The narrative is meticulously organized, transitioning from the advancements of AI and genomics to the more extensive institutional and societal implications of drug access and retail medicine. The book is essential reading for both healthcare professionals and engaged citizens due to his capacity to transform the technical into the tangible.

At its core, the book confronts questions of equity, innovation, and institutional readiness. It explores how big tech’s entry into clinical care challenges traditional models, how breakthrough therapies alter cost structures and ethical frameworks, and how public policy must evolve to ensure that technological advancement does not widen the gap between those with access and those without. Runge presents these themes not as abstract ideals, but as urgent and immediate realities, grounded in data, experience, and moral clarity.

The intellectual impact of The Great Healthcare Disruption is profound. It invites the reader to think critically about the systems we rely on—and to reimagine what those systems could become when guided by both innovation and conscience. Runge does not simply advocate for change; he illuminates its pathways, exposing the tensions between public good and private enterprise, innovation and regulation, hope and caution.

Ultimately, this book matters because it demands more than passive reading—it calls for participation. Marschall Runge writes with the conviction of someone who has lived inside the machinery of modern medicine and now urges us to take part in its reassembly. The Great Healthcare Disruption is essential reading for anyone who believes healthcare is not just a system, but a shared responsibility—and a defining challenge of our time.

About the Author

Marschall Runge

Marschall S. Runge, M.D., Ph.D., is the executive vice president for Medical Affairs at the University of Michigan, dean of the Medical School, and CEO of Michigan Medicine. He earned his doctorate in molecular biology at Vanderbilt University and his medical degree from Johns Hopkins School of Medicine, where he also completed a residency in internal medicine. He was a cardiology fellow at the Massachusetts General Hospital. He is the author of over 250 publications and holds five patents for novel approaches to health care. As a Texas native who spent fifteen years in North Carolina and an avid thriller reader, Runge has experienced so many you-can’t-make-this-up events that his transition to fiction was inevitable.